Anti-BMP15 Aptamer(Cat#: CTApt-1760)

This product is an aptamer which binds to BMP15 with an affinity of 50-200 nM.

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Summary

Specifications
Target Category Protein
Target BMP15
Alternative Names Bone Morphogenetic Protein 15; GDF9B; Growth/Differentiation Factor 9B; BMP-15; GDF-9B; ODG2; POF4; BMP15
Gene ID 9210
UniProt ID O95972
Target Overview This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure.
Type DNA
Length 50-100 nt
Affinity (Kd) 50-200 nM
Binding Conditions/Buffer 500 μl of 50 mM NaH2PO4, 300 mM NaCl, and 20 mM imidazole, pH 8.0
GC Content 44.87%
Molecular Weight 23645.4 g/mole
nmoles/OD260 1.211
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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