This is an aptamer development services to screening aptamers binds to the BMP2 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | BMP2 |
| Alternative Names | Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 2A; BMP2A; BMP-2A; SSFSC; BMP-2; BDA2; BMP2 |
| Gene ID | 650 |
| UniProt ID | P12643 |
| Target Overview | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |