Anti-BMPR1B aptamer SELEX Service(Cat#: CTApt-1769)
This is an aptamer development services to screening aptamers binds to the BMPR1B with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
BMPR1B |
| Alternative Names |
Bone Morphogenetic Protein Receptor Type 1B; Bone Morphogenetic Protein Receptor, Type IB; Bone Morphogenetic Protein Receptor Type-1B; BMP Type-1B Receptor; EC 2.7.11.30; BMPR-1B; CDw293; ALK6; Serine/Threonine Receptor Kinase; Activin Receptor-Like Kinase 6; CDw293 Antigen; EC 2.7.11; BMPR1B; ALK-6; BDA1D; AMDD; BDA2 |
| Gene ID |
658 |
| UniProt ID |
O00238 |
| Target Overview |
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
