Anti-BPGM aptamer SELEX Service(Cat#: CTApt-1782)
This is an aptamer development services to screening aptamers binds to the BPGM with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
BPGM |
| Alternative Names |
Bisphosphoglycerate Mutase; 2,3-Bisphosphoglycerate Mutase, Erythrocyte; 2,3-Bisphosphoglycerate Synthase; 2,3-Diphosphoglycerate Mutase; BPG-Dependent PGAM; DPGM; Testis Secretory Sperm-Binding Protein Li 202a; Erythrocyte 2,3-Bisphosphoglycerate Mutase; 2,3-Bisphosphoglycerate Mutase; EC 5.4.2.11; EC 5.4.2.4; ECYT8; BPGM |
| Gene ID |
669 |
| UniProt ID |
P07738 |
| Target Overview |
2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
