Anti-BRD2 aptamer SELEX Service(Cat#: CTApt-2015)

This is an aptamer development services to screening aptamers binds to the BRD2 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target BRD2
Alternative Names Bromodomain Containing 2; RING3; Really Interesting New Gene 3 Protein; Bromodomain-Containing Protein 2; BRD2 Intronic Transcript 1; KIAA9001; D6S113E; O27.1.1; FSRG1; NAT; Female Sterile Homeotic-Related Gene ; Bromodomain-Containing 2; BRD2-IT; RNF3; BRD2; FSH
Gene ID 6046
UniProt ID P25440
Target Overview This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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