Anti-BTK aptamer SELEX Service(Cat#: CTApt-1815)

This is an aptamer development services to screening aptamers binds to the BTK with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target BTK
Alternative Names Bruton Tyrosine Kinase; ATK; Bruton Agammaglobulinemia Tyrosine Kinase; Tyrosine-Protein Kinase BTK; Bruton'S Tyrosine Kinase; B-Cell Progenitor Kinase; EC 2.7.10.2; PSCTK1; AGMX1; BPK; XLA; Dominant-Negative Kinase-Deficient Brutons Tyrosine Kinase; Truncated Bruton Agammaglobulinemia Tyrosine Kinase; Agammaglobulinaemia Tyrosine Kinase; Agammaglobulinemia Tyrosine Kinase; EC 2.7.10; IGHD3; IMD1; BTK; AT
Gene ID 695
UniProt ID Q06187
Target Overview The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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