Anti-CD1C aptamer SELEX Service(Cat#: CTApt-2018)

This is an aptamer development services to screening aptamers binds to the CD1C with an affinity of 1nM~1μM.

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Lot Number

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Summary

Specifications
Target Category Protein
Target CD1C
Alternative Names CD1c Molecule; T-Cell Surface Glycoprotein CD1c; CD1C Antigen, C Polypeptide; CD1c Antigen; Differentiation Antigen CD1-Alpha-3; Cortical Thymocyte Antigen CD1C; BDCA1; CD1A; CD1C; CD1; R7
Gene ID 911
UniProt ID P29017
Target Overview This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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