Anti-CLDN7 Aptamer SELEX Service(Cat#: CTApt-720)

This is an aptamer development services to screening aptamers binds to the CLDN7 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target CLDN7
Alternative Names CLDN-7; CEPTRL2; CPETRL2; Hs.84359; claudin-1
Gene ID 1366
UniProt ID O95471
Target Overview This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc. Alternatively spliced transcript variants encoding different isoforms have been found.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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