This product is a customized aptamer which binds to Diclofenac with an affinity of 1-50 nM.
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| Target Category | Drug |
| Target | Diclofenac |
| Alternative Names | DCF |
| Target Overview | Diclofenac, sold under the brand name Voltaren, among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammatory diseases such as gout. It is taken by mouth or rectally in a suppository, used by injection, or applied to the skin. Improvements in pain last for as much as eight hours.It is also available in combination with misoprostol in an effort to decrease stomach problems. |
| Type | DNA |
| Length | 50-100 nt |
| Affinity (Kd) | 1-50 nM |
| Binding Conditions/Buffer | 100 mM NaCl, 20 mM Tris-HCl, 2 mM MgCl₂, 5 mM KCl, 1 mM CaCl₂, 0.02% Tween 20, pH 7.6 |
| GC Content | 51% |
| Molecular Weight | 22583 g/mole |
| nmoles/OD260 | 1.277 |