Anti-Escherichia coli Shiga Toxin-2 Aptamer(Cat#: CTWZ-0124-WZ52)

This product is an aptamer which binds to Escherichia coli Shiga Toxin-2 with a high affinity.

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Summary

Specifications
Target Category Protein
Target Shiga Toxin-2
Alternative Names STX2
Target Overview Shiga toxin (Stx) is the most significant cause of hemolytic uremic syndrome (HUS), which results in acute renal failure in children. Stx2 is firmly linked with the development of HUS as Shiga toxin- (Stx-) producing Escherichia coli (STEC) strains producing this toxin are frequently associated with HUS.
Chemical Modification 2'-fluoro pyrimidines
Type RNA
Species Reactivity Bacteria
Length <50 nt
Binding Conditions/Buffer 20 mM HEPES, 150 mM NaCl, and 5 mM MgCl2, pH 7.3
GC Content 43.90%
Molecular Weight 11932.8 g/mole
nmoles/OD260 2.474
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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