Anti-GRK3 Aptamer SELEX Service(Cat#: CTApt-1048)

This is an aptamer development services to screening aptamers binds to the GRK3 with an affinity of 1nM~1μM.

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Certificate of Analysis Lookup

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Summary

Specifications
Target Category Protein
Target GRK3
Alternative Names G Protein-Coupled Receptor Kinase 3; BARK2; Adrenergic, Beta, Receptor Kinase 2; Beta-Adrenergic Receptor Kinase 2; EC 2.7.11.15; Beta-ARK-2; ADRBK2; G-Protein-Coupled Receptor Kinase 3; EC 2.7.11; GRK3
Gene ID 157
UniProt ID P35626
Target Overview The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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