This product is an aptamer that binds to the Tat protein of HIV-2 with an affinity of 50-200 pM.
Target Category | Protein |
Target | HIV-2 Tat |
Target Overview | HIV-2 Tat is composed of 130 amino acids versus 86 amino acids for HIV-1 Tat. Apart from certain conserved regions, there is little homology between the two Tats. They also differ in their ability to trans-activate HIV-2 and HIV-1 long terminal repeat (LTR)-directed gene expression. |
Type | RNA |
Species Reactivity | Virus |
Length | 50-200 nt |
Affinity (Kd) | 50-200 pM |
Binding Conditions/Buffer | 50 mM Tris±HCl and 50 mM KCl, pH 7.8 |
GC Content | 55.26% |
Molecular Weight | 11454.84 g/mole |
nmoles/OD260 | 3.16 |