This product is a customized aptamer which binds to CBF1 with an affinity of 50-200 nM.
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| Target Category | Protein |
| Target | CBF1 |
| Alternative Names | C promoter binding factor 1; RBPJ; Recombination Signal Binding Protein For Immunoglobulin Kappa J Region ; RBPJK |
| Gene ID | 3516 |
| UniProt ID | Q06330 |
| Target Overview | CBF1 is a key transcription factor involved in Notch signaling, a pathway that is critical for inhibiting angiogenesis. |
| Type | DNA |
| Species Reactivity | Human |
| Length | 50-100 nt |
| Affinity (Kd) | 50-200 nM |
| Binding Conditions/Buffer | 100 mM Tris HCl, pH 8.0, 100 mM NaCl, 5 mM KCl, 1 mM MgCl₂, 0.1% Tween 20, 1 mg/mL BSA |
| GC Content | 54% |
| Molecular Weight | 22004.29 g/mole |
| nmoles/OD260 | 1.44 |