Anti-Human CD33 Aptamer(Cat#: CTMM-0124-LH15)

This product is an aptamer which binds to Human CD33 domain with an affinity of 1-50 nM.

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Summary

Specifications
Target Category Protein
Target CD33
Alternative Names CD33 Molecule; SIGLEC3; SIGLEC-3; P67; Sialic Acid-Binding Ig-Like Lectin 3; Myeloid Cell Surface Antigen CD33; CD33 Antigen (Gp67); FLJ00391; Gp67; Sialic Acid Binding Ig-Like Lectin 3; CD33 Molecule Transcript; CD33 Antigen; Siglec-3
Gene ID 945
UniProt ID P20138
Target Overview Enables protein phosphatase binding activity and sialic acid binding activity. Involved in several processes, including negative regulation of cytokine production; negative regulation of monocyte activation; and positive regulation of protein tyrosine phosphatase activity. Located in several cellular components, including Golgi apparatus; external side of plasma membrane; and peroxisome.
Type DNA
Species Reactivity Human
Length 50-100 nt
Affinity (Kd) 1-50 nM
Binding Conditions/Buffer 20 mM Tris HCl, 140 mM NaCl, 5 mM KCl, 1 mM MgCl2 and 1 mM CaCl2
GC Content 50.00%
Molecular Weight 23345.2 g/mole
nmoles/OD260 1.265
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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