This product is an aptamer which binds to the Human EPX with an affinity of 1-50 nM.
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| Target Category | Protein |
| Target | EPX |
| Alternative Names | Eosinophil Peroxidase; EPO; EPP; EPX-PEN; EPXD; EPER |
| Gene ID | 8288 |
| UniProt ID | P11678 |
| Target Overview | This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded preproprotein is proteolytically processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a gene cluster with other peroxidase genes on chromosome 17. Mutations in this gene result in eosinophil peroxidase deficiency. |
| Type | DNA |
| Species Reactivity | Human |
| Length | 50-100 nt |
| Affinity (Kd) | 1-50 nM |
| Binding Conditions/Buffer | 50 mM Tris, 1 M NaCl, 5 mM MgCl₂, 2 mM KCl, 0.01% v/v Tween 20, pH 9 |
| GC Content | 62.86% |
| Molecular Weight | 21885.20 g/mole |
| nmoles/OD260 | 1.45 |