Anti-Human ERβ Aptamer(Cat#: CTMM-0124-TT27)
This product is an aptamer which binds to the Human ERβ with an affinity of 1-50 nM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ESR2 |
| Alternative Names |
Estrogen Receptor 2; NR3A2; Nuclear Receptor Subfamily 3 Group A Member 2; Estrogen Receptor Beta; Oestrogen Receptor Beta; ER-Beta; ER-BETA; ESTRB; Erb; Estrogen Receptor 2 (ER Beta); Estrogen Receptor Beta 2; Estrogen Receptor Beta 4; ESR-BETA; ER Beta; ESRB; ODG8; ERB |
| Gene ID |
2100 |
| UniProt ID |
Q92731 |
| Target Overview |
This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. |
| Type |
RNA |
| Species Reactivity |
Human |
| Length |
50-100 nt |
| Affinity (Kd) |
1-50 nM |
| Binding Conditions/Buffer |
12 mM HEPES, 150 mM NaCl, and 10 mM MgCl₂, pH 7.6 |
| GC Content |
53.00% |
| Molecular Weight |
30680.63 g/mole |
| nmoles/OD260 |
1.08 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
