Name: Anti-Human GDF15 Aptamer
SKU: CTMM-0124-LH58
Rating: 5 (1 reviews)

Specifications

Target Category	Protein
Target	GDF15
Alternative Names	Growth Differentiation Factor 15; MIC-1; NAG-1; PTGFB; PLAB; MIC1; PDF; Prostate Differentiation Factor; Non-Steroidal Anti-Inflammatory Drug-Activated Gene-1; Placental Bone Morphogenetic Protein; Growth/Differentiation Factor 15; Macrophage Inhibitory Cytokine 1; NSAID-Activated Gene 1 Protein; NSAID-Regulated Gene 1 Protein; Placental TGF-Beta; GDF-15; NRG-1; NSAID (Nonsteroidal Anti-Inflammatory Drug)-Activated Protein 1; Macrophage Inhibitory Cytokine-1; PTGF-Beta
Gene ID	9518
UniProt ID	Q99988
Target Overview	This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress.
Type	DNA
Species Reactivity	Human; Rat
Length	<50 nt
Affinity (Kd)	1-50 nM
Binding Conditions/Buffer	PBS with 2 mM of MgCl_{2_{, pH=7.2}}
GC Content	25.53%
Molecular Weight	6045 g/mole
nmoles/OD260	4.478

Anti-Human GDF15 Aptamer(Cat#: CTMM-0124-LH58)

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