This product is an aptamer which binds to Human IgG Fc with an affinity of 50-200 nM.
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
| Target Category | Protein |
| Target | IgG Fc |
| Target Overview | The Fc portion of immunoglobulin G (IgG) is a horseshoe-shaped homodimer, which interacts with various effector proteins, including Fcγ receptors (FcγRs). |
| Chemical Modification | 2'-fluoro C (fC), 2'-hydroxy U (rU), 2'-deoxy U (dU), or 2'-O-methyl U (mU) |
| Type | RNA |
| Species Reactivity | Human |
| Length | <50 nt |
| Affinity (Kd) | 50-200 nM |
| Binding Conditions/Buffer | 145 mM NaCl, 5.4 mM KCl, 0.8 mM MgCl2, 1.8 mM CaCl2, and 20 mM Tris-HCl, pH 7.6 |
| GC Content | 56.00% |
| Molecular Weight | 7056.6 g/mole |
| nmoles/OD260 | 3.861 |