Anti-Human IL23A Aptamer(Cat#: CTMM-0124-RJ33)

This product is an aptamer which binds to Human IL23A with a high affinity.

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Summary

Specifications
Target Category Protein
Target IL23A
Alternative Names Interleukin 23 Subunit Alpha; SGRF; IL23P19; IL-23A; IL-23; P19; Interleukin-Six, G-CSF Related Factor; Interleukin 23, Alpha Subunit P19; Interleukin-23 Subunit Alpha; Interleukin-23 Subunit P19; IL-23 Subunit Alpha; IL-23p19; IL-23-A; JKA3 Induced Upon T-Cell Activation; Interleukin 23 P19 Subunit; IL23A
Gene ID 51561
UniProt ID Q9NPF7
Target Overview This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells.
Type RNA
Species Reactivity Human
Length 50-102 nt
Binding Conditions/Buffer 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES)-buffered (pH 7.5) saline containing tween-20 (HBS-T)
GC Content 39.51%
Molecular Weight 24274.3 g/mole
nmoles/OD260 1.089
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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