Anti-Human L1CAM Aptamer(Cat#: CTMM-0124-TT51)
This product is an aptamer which binds to the Human L1CAM with an affinity of 1-50 nM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
L1CAM |
| Alternative Names |
L1 Cell Adhesion Molecule; NCAM-L1; CAML1; Neural Cell Adhesion Molecule L1; CD171; MIC5; Antigen Identified By Monoclonal Antibody R1; N-CAM-L1; HSAS1; HSAS; MASA; SPG1; S10; CD171 Antigen; N-CAML1; HYCX |
| Gene ID |
3897 |
| UniProt ID |
P32004 |
| Target Overview |
The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. |
| Type |
DNA |
| Species Reactivity |
Human |
| Length |
50-100 nt |
| Affinity (Kd) |
1-50 nM |
| Binding Conditions/Buffer |
PBS with 4.5 g/L glucose, 5 mM MgCl₂, 1 mg/mL BSA, 0.1 mg/mL Herringsperm DNA |
| GC Content |
52.94% |
| Molecular Weight |
15963.40 g/mole |
| nmoles/OD260 |
2.08 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
