Name: Anti-Human MYC Aptamer
SKU: CTWZ-0124-WZ14
Rating: 5 (1 reviews)

Specifications

Target Category	Protein
Target	MYC
Alternative Names	MYC Proto-Oncogene, BHLH Transcription Factor; BHLHe39; MYCC; V-Myc Avian Myelocytomatosis Viral Oncogene Homolog; Class E Basic Helix-Loop-Helix Protein 39; Myc Proto-Oncogene Protein; Transcription Factor P64; Proto-Oncogene C-Myc; BHLHE39 ; C-Myc; Myc-Related Translation/Localization Regulatory Factor; Avian Myelocytomatosis Viral Oncogene Homolog; V-Myc Myelocytomatosis Viral Oncogene Homolog; C-MYC; MRTL
Gene ID	4609
UniProt ID	P01106
Target Overview	This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.
Type	DNA
Species Reactivity	Human
Length	50-100 nt
Affinity (Kd)	50-200 nM
Binding Conditions/Buffer	13.5 mM NaCl, 100 mM KCl, 0.22 mM Na₂HPO₄, 5 mM MgSO₄, 120 nM CaCl₂, 5 mM MgCl₂, 0.05% NP40, 20 mM HEPES, pH 7.25
GC Content	55.68%
Molecular Weight	26793.4 g/mole
nmoles/OD260	1.05

Anti-Human MYC Aptamer(Cat#: CTWZ-0124-WZ14)

Certificate of Analysis Lookup

Lot Number