This product is an aptamer which binds to Human Retinol binding protein 4 (RBP4) with an affinity of 200-1000 nM.
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| Target Category | Protein |
| Target | Retinol binding protein 4 (RBP4) |
| Alternative Names | Retinol Binding Protein 4; Plasma Retinol-Binding Protein; Retinol-Binding Protein |
| Gene ID | 5950 |
| UniProt ID | P02753 |
| Target Overview | RBP4 is a transporter of retinol. It is primarily synthesized in the liver and circulates in the bloodstream as a hepatokine. Due to its role in vision, RBP4 has been a drug target in ophthalmology research. |
| Type | DNA |
| Species Reactivity | Human |
| Length | <50 nt |
| Affinity (Kd) | 200-1000 nM |
| Binding Conditions/Buffer | 100 mM NaCl, 20 mM Tris-HCl, 2 mM MgCl₂, 5 mM KCl, 1 mM CaCl₂, 0.02 Tween-20, pH 7.6 |
| GC Content | 62.50% |
| Molecular Weight | 12576.19 g/mole |
| nmoles/OD260 | 2.53 |