Anti-Human SIRT1 Aptamer(Cat#: CTWZ-0124-WZ45)
This product is an aptamer which binds to human SIRT1 with an affinity of 200-1000 pM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
SIRT1 |
| Alternative Names |
Sirtuin 1; SIR2L1; NAD-Dependent Protein Deacetylase Sirtuin-1; NAD-Dependent Protein Deacylase Sirtuin-1; Regulatory Protein SIR2 Homolog 1; SIR2-Like Protein 1; Sirtuin (Silent Mating Type Information Regulation 2, S. Cerevisiae, Homolog) 1; Sirtuin (Silent Mating Type Information Regulation 2 Homolog) 1 (S. Cerevisiae); Sirtuin Type 1; EC 2.3.1.286; EC 2.3.1.-; SIR2alpha; HSIRT1; HSIR2; SIR2 |
| Gene ID |
23411 |
| UniProt ID |
Q96EB6 |
| Target Overview |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. |
| Type |
DNA |
| Species Reactivity |
Human |
| Length |
50-100 nt |
| Affinity (Kd) |
200-1000 pM |
| Binding Conditions/Buffer |
100 mM NaCl, 5 mM MgCl2, pH 7.4 |
| GC Content |
50.63% |
| Molecular Weight |
23919.6 g/mole |
| nmoles/OD260 |
1.161 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
