Anti-IL13 Aptamer SELEX Service(Cat#: CTApt-781)

This is an aptamer development services to screening aptamers binds to the IL13 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target IL13
Alternative Names Interleukin 13; IL-13; Interleukin-13; P600; Bronchial Hyperresponsiveness-1 (Bronchial Asthma); Allergic Rhinitis
Gene ID 3596
UniProt ID P35225
Target Overview This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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