Anti-Integrin α5β1 Aptamer(Cat#: CTMM-0422-MM255)

Name: Anti-Integrin α5β1 Aptamer
SKU: CTMM-0422-MM255
Rating: 5 (1 reviews)

This product is an aptamer which binds to the Integrin α5β1 with an affinity of <400 nM.

Certificate of Analysis Lookup

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Lot Number

Specifications

Target Category	Cell
Target	Integrin α5β1
Target Overview	α5β1, also known as the fibronectin receptor, is an integrin that binds to matrix macromolecules and proteinases and thereby stimulates angiogenesis. It is composed of α5 (ITGA5/CD49e) and β1 (ITGB1/CD29) subunits. It is the primary receptor for fibronectin.
Chemical Modification	DNA
Length	60-80 nt
Affinity (Kd)	<400 nM
Binding Conditions/Buffer	1 mM MgCl₂ & 0.5 mM CaCl₂2 in PBS (pH 7.4).
GC Content	0.7586
Molecular Weight	20749.2 g/mole
Extinction Coefficient	620700 L/(mole·cm)
nmoles/OD260	1.61