Anti-Interferon-Gamma Aptamer(Cat#: CTApt-M-1212)

This product is an aptamer which binds to the IFNG with an affinity of <100 nM.

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Specifications
Target Category Protein
Target IFNG
Alternative Names Interferon Gamma; Immune Interferon; IFN-Gamma; IMD69; IFG; IFI
Gene ID 3458
UniProt ID P01579
Target Overview This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases.
Chemical Modification DNA
Length 40-60 nt
Affinity (Kd) <100 nM
Binding Conditions/Buffer Salmon sperm DNA (0.1 mg/mL) and BSA (1 mg/mL) were added to the binding buffer (PBS) to reduce the background interference
GC Content 0.4746
Molecular Weight 18001.76 g/mole
Extinction Coefficient 585100 L/(mole·cm)
nmoles/OD260 1.71

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