Anti-Interferon-y Aptamer(Cat#: CTApt-M-1656)

This product is an aptamer which binds to the IFN-y with an affinity of <20 nM.

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Summary

Specifications
Target Category Protein
Target IFN-y
Alternative Names Interferon Gamma; Immune Interferon; IFN-Gamma; IMD69; IFG; IFI
Gene ID 3458
UniProt ID P01579
Target Overview This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mutations in this gene are associated with an increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases.
Chemical Modification 2'-NH2-RNA
Length 60-80 nt
Affinity (Kd) <20 nM
Binding Conditions/Buffer Binding Mixture: PBS (138 mM NaC1, 2.7 mM KCl, 8.1 mM Na2HPO4, and 1.1 mM KH2PO4, pH 7.4) containing 1 mM Mg2+ ions and 0.01% human serum albumin.
GC Content 55.71%
Molecular Weight 38579.5 g/mole
Extinction Coefficient 710100 L/(mole·cm)
nmoles/OD260 1.41
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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