This product is an aptamer which binds to the L-Selectin binding to sialyl Lewis X with an affinity of <20 nM.
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| Target Category | Protein |
| Target | L-Selectin binding to sialyl Lewis X |
| Chemical Modification | DNA |
| Length | 40-60 nt |
| Affinity (Kd) | <20 nM |
| Binding Conditions/Buffer | 20 mM Hepes, 111 mM NaCl, 1 mM CaCl2, 1 mM MgCl2, 5 mM KCl, 8.9 mM NaOH final pH 8) and 1% globulin-free BSA. |
| GC Content | 0.4694 |
| Molecular Weight | 15113.89 g/mole |
| Extinction Coefficient | 481400 L/(mole·cm) |
| nmoles/OD260 | 2.08 |
This aptamer is a gemExcellentOutstanding product! It has significantly improved the precision and reliability of our flow cytometry assays.
It's robust, and the manufacturer's technical support has been incredibly helpfulExcellentIt's reliable, and the technical support from the manufacturer was meaningful. It would be great to see more published protocols and application notes to help new users get started.
The specificity and binding affinity are top-notchExcellentIt has consistently outperformed other aptamers we've used in the past, and it's become the go-to choice in our lab.