This is an aptamer development services to screening aptamers binds to the LPAR1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | LPAR1 |
| Alternative Names | Lysophosphatidic Acid Receptor 1; LPA1; Endothelial Differentiation, Lysophosphatidic Acid G-Protein-Coupled Receptor, 2; Lysophosphatidic Acid Receptor Edg-2; LPA Receptor 1; Mrec1.3; Rec.1.3; Gpcr26; GPR26; Edg-2; Vzg-1; LPA-1; EDG2; Ventricular Zone Gene 1; LPAR1; VZG1 |
| Gene ID | 1902 |
| UniProt ID | Q92633 |
| Target Overview | The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |