This product is an aptamer which binds to the Lipopolysaccharide (LPS) with an affinity of <20 nM.
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| Target Category | Small Organic |
| Target | Lipopolysaccharide (LPS) |
| Target Overview | Lipopolysaccharides (LPS) are important outer membrane components of gram-negative bacteria. They are large amphipathic glycoconjugates that typically consist of a lipid domain (hydrophobic) attached to a core oligosaccharide and a distal polysaccharide. |
| Chemical Modification | DNA |
| Length | 80-100 nt |
| Affinity (Kd) | <20 nM |
| Binding Conditions/Buffer | 50 mM Tris-acetate, pH 8.2. |
| GC Content | 0.6163 |
| Molecular Weight | 26426.08 g/mole |
| Extinction Coefficient | 803400 L/(mole·cm) |
| nmoles/OD260 | 1.24 |
It consistently outperforms traditional antibodiesExcellentThis aptamer has significantly enhanced our experiments on bacterial LPS detection. It's highly specific and reproducible, making our research more reliable.
Impressive specificity and sensitivityExcellentAs a PhD student studying bacterial infections, I find this aptamer indispensable. It's robust and works well across a range of conditions in our experiments.
It's proven to be robust and adaptableExcellentWe switched to using this aptamer after facing issues with other assays. It's reliable and consistent, giving us confidence in our research findings.
It's effective and affordable, making it accessible for various research budgetsExcellentThe technical support team was incredibly helpful in guiding us through the initial setup. The aptamer itself is top-notch. It's highly specific and doesn't cross-react with structurally similar molecules.