Anti-Methylene blue Aptamer(Cat#: CTApt-2565)
This product is an aptamer which binds to the Methylene blue with an affinity of <300 nM.
Specific Inquiry 
Specifications
| Target Category |
Small Organic |
| Target |
Methylene blue |
| Alternative Names |
methylene blue; 61-73-4; Basic blue 9; Methylthioninium chloride; Swiss Blue |
| Target Overview |
Methylene Blue is a synthetic basic dye. Methylene blue stains to negatively charged cell components like nucleic acids; when administered in the lymphatic bed of a tumor during oncologic surgery, methylene blue may stain lymph nodes draining from the tumor, thereby aiding in the visual localization of tumor sentinel lymph nodes. When administered intravenously in low doses, this agent may convert methemoglobin to hemoglobin. |
| Chemical Modification |
DNA |
| Length |
40-60 nt |
| Affinity (Kd) |
<300 nM |
| Binding Conditions/Buffer |
20 mM HEPES, 1 M NaCl, 10 mM MgCl2, 5 mM KCl, pH 7.5 |
| GC Content |
61% |
| Molecular Weight |
14223.2 |
| nmoles/OD260 |
2.073 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
