Anti-Mouse HAVCR2 Aptamer(Cat#: CTWZ-0124-WZ22)
This product is an aptamer which binds to mouse HAVCR2 with a high affinity.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
HAVCR2 |
| Alternative Names |
Hepatitis A Virus Cellular Receptor 2; TIMD3; TIM3; CD366; T-Cell Immunoglobulin And Mucin Domain-Containing Protein 3; T-Cell Immunoglobulin Mucin Family Member 3; T-Cell Immunoglobulin Mucin Receptor 3; T-Cell Membrane Protein 3; FLJ14428; HAVcr-2; TIMD-3; Tim-3; TIM-3; T-Cell Immunoglobulin And Mucin Domain 3; T Cell Immunoglobulin Mucin 3; Kidney Injury Molecule-3; CD366 Antigen; KIM-3; SPTCL |
| Gene ID |
84868 |
| UniProt ID |
Q8TDQ0 |
| Target Overview |
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. |
| Chemical Modification |
2'-fluoro pyrimidines |
| Type |
RNA |
| Species Reactivity |
Mouse |
| Length |
50-100 nt |
| Binding Conditions/Buffer |
150 nmol/L NaCl, 20 mmol/L KCl, and 20 mmol/L HEPES |
| GC Content |
56.41% |
| Molecular Weight |
23479.2 g/mole |
| nmoles/OD260 |
1.226 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
