This product is an aptamer which binds to the p53 with a high affinity.
Target Category | Protein |
Target | p53 |
Chemical Modification | 2'-O-Me-RNA |
Length | 60-80 nt |
Affinity (Kd) | N/A |
Binding Conditions/Buffer | 0.15 mM Hepes [pH 7.4], 0.3 mM KCl, 6 uM dithiothreitol [DTT], 6 uM MgCl2, 1.1 uM ethylenediaminetetraacetic acid [EDTA], 6% glycerol, and 3 uM phenylmethanesulfonyl fluoride [PMSF]. |
GC Content | 0.48 |
Molecular Weight | 25257.7 g/mole |
Extinction Coefficient | 753400 L/(mole·cm) |
nmoles/OD260 | 1.33 |
We are planning to order more for our ongoing projectsExcellentOur lab has recently adopted the anti-p53 RNA aptamer, and we have seen a noticeable improvement in the reliability of our data.
Proven to be an invaluable tool in our studiesExcellentIts versatility in various experimental setups, such as flow cytometry and fluorescence imaging, has made it a go-to reagent in our lab. The cost-effectiveness of this aptamer compared to other options on the market is an additional advantage.
I am thoroughly impressedExcellentWe incorporated the anti-p53 RNA aptamer into our immunoprecipitation experiments, and the results have been outstanding. The aptamer's specificity ensures clean and specific pull-downs.