Anti-Prion Protein Aptamer(Cat#: CTApt-M-1919)
This product is an aptamer which binds to the Prion with an affinity of <100 nM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
Prion |
| Target Overview |
Prions are misfolded proteins with the ability to transmit their misfolded shape onto normal variants of the same protein. They characterize several fatal and transmissible neurodegenerative diseases in humans and many other animals. |
| Chemical Modification |
2'-NH2-RNA |
| Length |
80-100 nt |
| Affinity (Kd) |
<100 nM |
| Binding Conditions/Buffer |
Binding Buffer (8um urea, 20 mm sodium phosphate, 500 mm sodium chloride (pH 7.8)) Selection Buffer (155 mM NaCl, 1.1 mM KH2PO4, 3.0 mM Na2HPO4, 1.0 mM MgCl2 (pH 7.4)) |
| GC Content |
0.5698 |
| Molecular Weight |
42720.3 g/mole |
| Extinction Coefficient |
889500 L/(mole·cm) |
| nmoles/OD260 |
1.12 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
