Anti-PTH Aptamer SELEX Service(Cat#: CTApt-823)

This is an aptamer development services to screening aptamers binds to the PTH with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target PTH
Alternative Names Parathyroid Hormone; Parathormone; Parathyrin; Preproparathyroid Hormone; Parathyroid Hormone 1; Prepro-PTH; PTH1; FIH1; PTH
Gene ID 5741
UniProt ID P01270
Target Overview This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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