Anti-PTK6 aptamer SELEX Service(Cat#: CTApt-1844)

This is an aptamer development services to screening aptamers binds to the PTK6 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target PTK6
Alternative Names Protein Tyrosine Kinase 6; BRK; PTK6 Protein Tyrosine Kinase 6; Tyrosine-Protein Kinase BRK; Protein-Tyrosine Kinase 6; Breast Tumor Kinase; EC 2.7.10.2; Protein-Tyrosine Kinase BRK; EC 2.7.10; PTK6
Gene ID 5753
UniProt ID Q13882
Target Overview The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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