This product is an aptamer which binds to the Ricin Toxin with an affinity of <50 nM.
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| Target Category | Small Organic |
| Target | Ricin Toxin |
| Target Overview | Ricin is a lectin (a carbohydrate-binding protein) and a highly potent toxin produced in the seeds of the castor oil plant, Ricinus communis. The median lethal dose (LD50) of ricin for mice is around 22 micrograms per kilogram of body weight via intraperitoneal injection. |
| Chemical Modification | DNA |
| Length | 80-100 nt |
| Affinity (Kd) | <50 nM |
| Binding Conditions/Buffer | Running Buffer for Capillary Electrophoresis: 20 mM HEPES (pH 7.1), 40 mM NaCl, 5 mM KCl, 1 mM CaCl22, and 1 mM MgCl2. Incubated at room temperature. |
| GC Content | 0.5698 |
| Molecular Weight | 26766.37 g/mole |
| Extinction Coefficient | 837700 L/(mole·cm) |
| nmoles/OD260 | 1.19 |