Anti-Saccharomyces cerevisiae G6PD Aptamer(Cat#: CTMM-0124-LH25)

This product is an aptamer which binds to Saccharomyces cerevisiae G6PD domain with an affinity of 200-1000 nM.

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Summary

Specifications
Target Category Protein
Target Saccharomyces cerevisiae G6PD
Alternative Names Glucose-6-Phosphate Dehydrogenase; G6PD1; Glucose-6-Phosphate 1-Dehydrogenase; EC 1.1.1.49; Epididymis Secretory Sperm Binding Protein
Gene ID 2539
UniProt ID P11413
Target Overview This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene.
Type DNA
Species Reactivity Yeast
Length <50 nt
Affinity (Kd) 200-1000 nM
Binding Conditions/Buffer PBS, 0.15 M NaCl, 20 mM phosphate buffer, 37°C, pH=7.2
GC Content 18.75%
Molecular Weight 9242.2 g/mole
nmoles/OD260 2.896
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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