Anti-TGFBR1 Aptamer SELEX Service(Cat#: CTApt-2354)
This is an aptamer development services to screening aptamers binds to the TGFBR1 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
TGFBR1 |
| Alternative Names |
Transforming Growth Factor Beta Receptor 1; ALK-5; ALK5; Activin A Receptor Type II-Like Protein Kinase Of 53kD; Transforming Growth Factor-Beta Receptor Type I; Activin A Receptor Type II-Like Kinase, 53kDa; Serine/Threonine-Protein Kinase Receptor R4; Transforming Growth Factor Beta Receptor I; Activin Receptor-Like Kinase 5; TGF-Beta Receptor Type-1; EC 2.7.11.30; TbetaR-I; ACVRLK4; TGFR-1; TBR-I; SKR4; TBRI ; Mutant Transforming Growth Factor Beta Receptor I; Multiple Self-Healing Squamous Epithelioma; TGF-Beta Type I Receptor; TGF-Beta Receptor Type I; EC 2.7.11; TGFBR; LDS1A; LDS2A; AAT5; ESS1; LDS1; MSSE |
| Gene ID |
7046 |
| UniProt ID |
P36897 |
| Target Overview |
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
