Anti-TIMP1 Aptamer SELEX Service(Cat#: CTApt-843)
This is an aptamer development services to screening aptamers binds to the TIMP1 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
TIMP1 |
| Alternative Names |
TIMP Metallopeptidase Inhibitor 1; Tissue Inhibitor Of Metalloproteinases 1; Fibroblast Collagenase Inhibitor; Metalloproteinase Inhibitor 1; Collagenase Inhibitor; TIMP-1; CLGI; TIMP; EPA; EPO; Tissue Inhibitor Of Metalloproteinase 1 (Erythroid Potentiating Activity, Collagenase Inhibitor); Epididymis Secretory Sperm Binding Protein; Erythroid Potentiating Activity; Erythroid-Potentiating Activity; TIMP1; HCI |
| Gene ID |
7076 |
| UniProt ID |
P01033 |
| Target Overview |
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
