Anti-TNFRSF17 aptamer SELEX Service(Cat#: CTApt-1847)

This is an aptamer development services to screening aptamers binds to the TNFRSF17 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target TNFRSF17
Alternative Names TNF Receptor Superfamily Member 17; BCM; Tumor Necrosis Factor Receptor Superfamily Member 17; B-Cell Maturation Protein; TNFRSF13A; CD269; BCMA; Tumor Necrosis Factor Receptor Superfamily, Member 17; B Cell Maturation Antigen; B-Cell Maturation Factor; CD269 Antigen; TNFRSF17
Gene ID 608
UniProt ID Q02223
Target Overview The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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