This product is an aptamer which binds to the Trypanosoma brucei with an affinity of <1 nM.
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| Target Category | Cell |
| Target | Trypanosoma brucei |
| Alternative Names | T. brucei |
| Target Overview | Trypanosoma brucei is a species of parasitic kinetoplastid belonging to the genus Trypanosoma. This parasite is the cause of vector-borne diseases of vertebrate animals, including humans, carried by species of tsetse fly in sub-Saharan Africa. In humans T. brucei causes African trypanosomiasis, or sleeping sickness. In animals it causes animal trypanosomiasis, also called nagana in cattle and horses. |
| Chemical Modification | RNA |
| Length | 80-100 nt |
| Affinity (Kd) | <1 nM |
| Binding Conditions/Buffer | 20 mM NaxHyPO4 (pH 7.4),2 mM MgCl2,130 mM NaCl,5 mM KCl, 20 mM glucose,0.2 mM β-mercaptoethanol). |
| GC Content | 0.6353 |
| Molecular Weight | 27369.42 g/mole |
| Extinction Coefficient | 805600 L/(mole·cm) |
| nmoles/OD260 | 1.24 |
Aptamers run seamlessly in my assaysExcellentFrom the time I started using this aptamer, it has worked consistently. No more worries about experimental variability and the data obtained is very reliable. As well as the clear and concise instructions provided make using this aptamer a breeze.
Kudos on this outstanding productExcellentAfter trying different aptamers, I can confidently say that this aptamer outperforms the competition. The aptamer significantly increased the sensitivity of my test.
This aptamer performs very well in isolating Trypanosoma bruceiExcellentThe results were clean and consistent, making my research simpler. Specificity is top notch and experimental reproducibility is excellent. Will be purchasing more!