This is an aptamer development services to screening aptamers binds to the TUBB3 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | TUBB3 |
| Alternative Names | Tubulin Beta 3 Class III; Class III Beta-Tubulin; Tubulin Beta-3 Chain; Tubulin Beta-4 Chain; Tubulin Beta-III; Tubulin, Beta 3; CFEOM3A; CFEOM3; Beta-4; TUBB4; Fibrosis Of Extraocular Muscles, Congenital, 3; CDCBM1; CDCBM; FEOM3; TUBB3 |
| Gene ID | 10381 |
| UniProt ID | Q13509 |
| Target Overview | This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |