Anti-VCAM1 Aptamer(Cat#: CTApt-M-730)

This product is an aptamer which binds to the VCAM1 with an affinity of <20 nM.

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5’ Modification
 
3’ Modification
 
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Summary

Specifications
Target Category Protein
Target VCAM1
Alternative Names Vascular Cell Adhesion Molecule 1 ; CD106; Vascular Cell Adhesion Protein 1 ; CD106 Antigen; INCAM-100; V-CAM 1 ; VCAM-1
Gene ID 7412
UniProt ID P40763
Target Overview This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene.
Chemical Modification 2'F-RNA
Length 20-40 nt
Affinity (Kd) <20 nM
GC Content 0.54
Molecular Weight 11927.8
nmoles/OD260 2.469
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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