This product is an anti-Porcine Complement C3a/C3a des Arg Monoclonal antibody (CTJS-90) generated from the Mouse. The antibody can be used for WB; ELISA; IP; FuncS.
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| Clonality | Monoclonal |
| Clone | CTJS-90 |
| Host Animal | Mouse |
| Isotype | IgG2b, κ |
| Immunogen | Purified porcine C3a |
| Species Reactivity | Porcine |
| Applications | WB; ELISA; IP; FuncS |
| Application Notes | The optimal working dilutions should be determined by the end user. |
| Specificity | This antibody reacts with Porcine complement C3a/C3a des Arg. |
| Purity | ≥95% as determined by SDS-PAGE |
| Format | Liquid |
| Size | 100ug |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles. |
| Type | Primary Antibody |
| Target Name | C3a |
| Alternative Names | Complement C3a; C3a des-Arg |
| Gene ID | 397072 |
| UniProt ID | P01025 |
| Introduction | Complement C3a is a 77 residue anaphylatoxin formed by the cleavage of complement component 3. C3a can bind to the C3a receptor induce responses. C3a is an effector of the complement system with a range of functions including T cell activation and survival, angiogenesis stimulation, chemotaxis, mast cell degranulation, and macrophage activation. C3a desArg is formed when the C-terminal arginine residue is cleaved off by serum carboxypeptidase B from C3a. C3a desArg binds to the C5L2 receptor inducing a lowered inflammatory function. |