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Native™ Human Anti-Membrane Protein Antibody Discovery

With seasoned expert team and vast experience, Creative Biolabs now provides integrated service of fully human anti-membrane protein antibody discovery based on our exclusive Native™ platform.

Native™ Human Anti-Membrane Protein Antibody Discovery Membrane proteins, such as GPCRs and ion channels, participate in many key physiological activities. Monoclonal anti-membrane protein antibodies for treatment of autoimmune diseases, transplantation side effects and cancers in clinic now exert tremendous medical impacts in recent years. Till now, more than 50 monoclonal antibodies have been approved in market, with numerous candidates under development stage. However, to obtain superior antibodies against membrane proteins is very challenging. Some conventional approaches (e.g. hybridomas, phage display) may be restricted in many aspects, for instance, small candidate pool, low efficiency, species limitation, loss of native VH-VL pairs, etc. After years of efforts and exploration, Creative Biolabs has successfully established a cutting-edge Native™ Antibody Discovery Platform as a promising solution.

As is known, B cells are responsible for antibody secretion in humoral immune responses. However, there are only a small fraction of them (usually less than 1%) that are capable of specific antigen recognition. Based on innovative antigen-specific B cell cytometry, we can isolate the particular population of antigen-specific B cells, creating a high-quality candidate pool for raising clones with highest binding affinity and native format at one time.

Native™ Human Anti-Membrane Protein Antibody Discovery

Advantages of Native™ Human Anti-Membrane Protein Antibody Discovery


Creative Biolabs has been a long-time pioneer in tailoring high-specificity, high-affinity antibodies targeting various membrane proteins. We provide one-stop services from membrane protein immunogen preparation to downstream antibody production and development. Regarding our Native™ platform, we provide a variety of host species to fulfill customers' demands:


Please feel free to contact us for more details, and we will be here for you 24/7.

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45-1 Ramsey Road, Shirley, NY 11967, USA
Call us at:
USA: 1-631-381-2994
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Fax: 1-631-207-8356
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