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Native™ Sheep Anti-Membrane Protein Antibody Discovery

With skillful scientific teams and world-leading technologies in membrane protein production and antibody discovery, Creative Biolabs now offers innovative sheep anti-membrane protein antibody discovery service based on our exclusive Native™ platform to our worldwide clients.

Native™ Sheep Anti-Membrane Protein Antibody Discovery It has been proven that membrane proteins participate in a wide range of important biophysical activities like cell growth, cell-cell communication, cell signaling transduction, migration, etc. They play significant roles in diverse disease. As is known, membrane proteins represent over 50% of current medical targets, and anti-membrane protein antibody drugs have been increasingly popular in recent years. Antibody development against membrane proteins is a very challenging task. Conventional approaches (e.g. hybridomas, phage display) may be restricted in many aspects, for instance, small candidate pool, low efficiency, species limitation, loss of native VH-VL pairs, etc. After years of devotion, Creative Biolabs has successfully built up an exclusive Native™ Antibody Discovery Platform that is specifically designed for cell membrane targets.

Sheep is considered as one of the most widely used host species for raising antibodies. First, sheep possesses a large volume of antiserum, which makes them an appropriate option for large-scale antibody production. This also allows researchers to obtain total antibodies from a single sheep, thus avoiding individual variabilities. Second, sheep demonstrates greater immune sensitivity, enabling a much wider range of epitope recognition in comparison to other host species. Third, antibodies raised from immunized sheep generally display higher specificity and affinity than standard mouse/rat ones, which indicate a greater potential for biomedical, veterinary, and agricultural purposes. So far, sheep anti-membrane protein antibodies with high specificity and affinity have proved to be ideal clinical leads suitable for diagnosis, prevention, and treatment of multiple life-threatening bacterial infections.

Native™ Sheep Anti-Membrane Protein Antibody Discovery

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As a look-forward research institution and service provider, Creative Biolabs has gained extensive experience in developing first-class antibodies against a broad range of membrane proteins in one-stop pipeline. In particular, we provide follow host species available for your selection. Please feel free to contact us for more details.


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