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Native™ Sheep Anti-Membrane Protein Antibody Discovery

With skillful scientific teams and world-leading technologies in membrane protein production and antibody discovery, Creative Biolabs now offers innovative sheep anti-membrane protein antibody discovery service based on our exclusive Native™ platform to our worldwide clients.

Native™ Sheep Anti-Membrane Protein Antibody Discovery It has been proven that membrane proteins participate in a wide range of important biophysical activities like cell growth, cell-cell communication, cell signaling transduction, migration, etc. They play significant roles in diverse disease. As is known, membrane proteins represent over 50% of current medical targets, and anti-membrane protein antibody drugs have been increasingly popular in recent years. Antibody development against membrane proteins is a very challenging task. Conventional approaches (e.g. hybridomas, phage display) may be restricted in many aspects, for instance, small candidate pool, low efficiency, species limitation, loss of native VH-VL pairs, etc. After years of devotion, Creative Biolabs has successfully built up an exclusive Native™ Antibody Discovery Platform that is specifically designed for cell membrane targets.

Sheep is considered as one of the most widely used host species for raising antibodies. First, sheep possesses a large volume of antiserum, which makes them an appropriate option for large-scale antibody production. This also allows researchers to obtain total antibodies from a single sheep, thus avoiding individual variabilities. Second, sheep demonstrates greater immune sensitivity, enabling a much wider range of epitope recognition in comparison to other host species. Third, antibodies raised from immunized sheep generally display higher specificity and affinity than standard mouse/rat ones, which indicate a greater potential for biomedical, veterinary, and agricultural purposes. So far, sheep anti-membrane protein antibodies with high specificity and affinity have proved to be ideal clinical leads suitable for diagnosis, prevention, and treatment of multiple life-threatening bacterial infections.

Native™ Sheep Anti-Membrane Protein Antibody Discovery

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As a look-forward research institution and service provider, Creative Biolabs has gained extensive experience in developing first-class antibodies against a broad range of membrane proteins in one-stop pipeline. In particular, we provide follow host species available for your selection. Please feel free to contact us for more details.



All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.

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