Recombinant Anti-B cell lymphoma A20-HL Idiotype x Anti-CD3 Bispecific Antibody (scFv-CH3) contains two chains. The anti-B cell lymphoma A20-HL Idiotype scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-CD3 scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can block cell adhesion. It is designed for the research of B cell lymphoma therapy.
Specifications
Targets
B cell lymphoma A20-HL Idiotype & CD3
Target 1
B cell lymphoma A20-HL Idiotype
Application
FuncS; Promising therapeutic agent
Related Disease
B cell lymphoma
Targets
Target 1
B cell lymphoma A20-HL Idiotype
Alternative Names
B cell lymphoma A20-HL Idiotype; B cell lymphoma; A20-HL ; Idiotype; Id
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3; AI504783
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