Home > Products > B cell lymphoma A20-HL Idiotype & CD3 > Recombinant Anti-B cell lymphoma A20-HL Idiotype x Anti-CD3 Bispecific Antibody (scFv4-Ig)

Recombinant Anti-B cell lymphoma A20-HL Idiotype x Anti-CD3 Bispecific Antibody (scFv4-Ig)  (FVTIG-015)

Recombinant Anti-B cell lymphoma A20-HL Idiotype x Anti-CD3 Bispecific Antibody (scFv4-Ig) is an appended IgG format, which includes four scFv moieties at the N-termini of the constant regions. It is a bivalent homodimer, in which one anti-B cell lymphoma A20-HL Idiotype scFv is fused to the CH1 domain of a heavy chain and another anti-CD3 scFv to the CL domain of a light chain, or vice versa. The resulting leads to 2+2 antigen-binding valency. This BsAb can block cell adhesion. It is designed for the research of B cell lymphoma therapy.

Specifications
Targets
B cell lymphoma A20-HL Idiotype & CD3
Type
Appended IgGs
Species Reactivity
Mouse
Target 1
B cell lymphoma A20-HL Idiotype
Host Animal 1
Rat
Target 2
CD3
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
B cell lymphoma
Targets
Target 1
B cell lymphoma A20-HL Idiotype
Alternative Names
B cell lymphoma A20-HL Idiotype; B cell lymphoma; A20-HL; Idiotype; Id
Target 2
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3; AI504783
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