Recombinant Anti-BAFF x Anti-B7RP1 Bispecific Antibody (scDiabody-CH3) is a fusion protein of two scDiabodies connected together by a CH3 region. In single-chain Diabodies, an additional connecting linker is introduced between chains of the anti-BAFF/anti-B7RP1 diabody. The scDiabody with two specificities is fused to each of the CH3 chains to extend half-life. This BsAb can bind and inactivate two ligands simultaneously. It can inhibit B cell survival and T cell costimulation. It is designed for the research of Systemic lupus erythematosus (SLE) therapy.
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